FCT
Designação do projeto | Projeto VALORIZEBYPRODUCTS – Eficácia pré-clínica do sulforafano ou do extrato total de Brássicas: uma estratégia para combater a obesidade e valorizar os subprodutos de Brássicas

Código do projeto | POCI-01-0145-FEDER-029152 / PTDC/ASP-HOR/29152/2017

Objetivo temático| Reforçar a investigação, o desenvolvimento tecnológico e a inovação.

Região de intervenção | Norte | Centro

Instituição proponente | UNIVERSIDADE DE TRAS OS MONTES E ALTO DOURO

Instituição participante | CENTRO DE NEUROCIÊNCIAS E BIOLOGIA CELULAR

Data de início | 1 de Junho de 2018

Data de conclusão | 28 de Fevereiro de 2022

Custo total elegível | 235.948,90€

Custo total elegível UTAD | 194.423,90€

Resumo:

Sulforaphane (SFN) is an isothiocyanate found in Brassica vegetables. The use of SFN for obesity treatment has been investigated with promising results. Brassicas production in the European Union and Portugal represents large amounts of byproducts with negative economic and environmental impacts. The exploitation of these byproducts for the extraction of SFN or used as a whole extract could be a strategy to follow with interest to stakeholders such as Nutrigreen, a partner in this project. This project aims to fight obesity while adding value to Brassica byproducts. A whole extract will be obtained from Brassica byproducts and its efficacy will be evaluated first in cell lines and later in an animal model of obesity. The efficacy of SFN commercially available will also be evaluated. The results will determine the way to go: whole extract or SFN extraction from Brassica byproducts to be used in the form of dietary supplements which may be employed for prevention or treatment of obesity.